Biological sensorimotor systems process information through spatially organized, functionally specialized modules. A canonical example is the rodent barrel cortex, in which each vibrissa (whisker) projects to a dedicated cortical column, forming a precise somatotopic map. This anatomical organization stands in stark contrast to the architectures of most artificial neural networks, which are typically monolithic or rely on globally routed mixture-of-experts (MoE) mechanisms. In this work, we introduce a brain-inspired modular architecture that treats the barrel cortex as a biologically constrained instantiation of an expert system. Each module (or "expert") corresponds to a cortical column composed of multiple neuron subtypes spanning vertical cortical layers.

The results described in Section 4.2 were obtained with a fixed choice on the power spectral

While modern AI continues to advance, the biological brain remains the pinnacle of neural networks in its robustness, adaptability, and efficiency. This review explores an AI architectural path inspired by the brain's structure, particularly the minicolumn hypothesis, which views the neocortex as a distributed system of repeated modules - a structure we connect to collective intelligence (CI). Despite existing work, there is a lack of comprehensive reviews connecting the cortical column to the architectures of repeated neural modules. This review aims to fill that gap by synthesizing historical, theoretical, and methodological perspectives on neural module repetition. We distinguish between architectural repetition - reusing structure - and parameter-shared module repetition, where the same functional unit is repeated across a network. The latter exhibits key CI properties such as robustness, adaptability, and generalization. Evidence suggests that the repeated module tends to converge toward a generalist module: simple, flexible problem solvers capable of handling many roles in the ensemble. This generalist tendency may offer solutions to longstanding challenges in modern AI: improved energy efficiency during training through simplicity and scalability, and robust embodied control via generalization. While empirical results suggest such systems can generalize to out-of-distribution problems, theoretical results are still lacking. Overall, architectures featuring module repetition remain an emerging and unexplored architectural strategy, with significant untapped potential for both efficiency, robustness, and adaptiveness. We believe that a system that adopts the benefits of CI, while adhering to architectural and functional principles of the minicolumns, could challenge the modern AI problems of scalability, energy consumption, and democratization.

In the traditional understanding of the neocortex, sensory information flows up a hierarchy of regions, with each level processing increasingly complex features. Information also flows down the hierarchy via a different set of connections. Although the hierarchical model has significant support, many anatomical connections do not conform to the standard hierarchical interpretation. In addition, hierarchically arranged regions sometimes respond in parallel, not sequentially as would occur in a hierarchy. This and other evidence suggests that two regions can act in parallel and hierarchically at the same time. Given this flexibility, the word "heterarchy" might be a more suitable term to describe neocortical organization. This paper proposes a new interpretation of how sensory and motor information is processed in the neocortex. The key to our proposal is what we call the "Thousand Brains Theory", which posits that every cortical column is a sensorimotor learning system. Columns learn by integrating sensory input over multiple movements of a sensor. In this view, even primary and secondary regions, such as V1 and V2, can learn and recognize complete 3D objects. This suggests that the hierarchical connections between regions are used to learn the compositional structure of parent objects composed of smaller child objects. We explain the theory by examining the different types of long-range connections between cortical regions and between the neocortex and thalamus. We describe these connections, and then suggest the specific roles they play in the context of a heterarchy of sensorimotor regions. We also suggest that the thalamus plays an essential role in transforming the pose between objects and sensors. The novel perspective we argue for here has broad implications for both neuroscience and artificial intelligence.

Achieving General Artificial Intelligence (AGI) has long been a grand challenge in the field of AI, and brain-inspired computing is widely acknowledged as one of the most promising approaches to realize this goal. This paper introduces a novel brain-inspired AI framework, Orangutan. It simulates the structure and computational mechanisms of biological brains on multiple scales, encompassing multi-compartment neuron architectures, diverse synaptic connection modalities, neural microcircuits, cortical columns, and brain regions, as well as biochemical processes including facilitation, feedforward inhibition, short-term potentiation, and short-term depression, all grounded in solid neuroscience. Building upon these highly integrated brain-like mechanisms, I have developed a sensorimotor model that simulates human saccadic eye movements during object observation. The model's algorithmic efficacy was validated through testing with the observation of handwritten digit images.

This paper proposes a new approach to Machine Learning (ML) that focuses on unsupervised continuous context-dependent learning of complex patterns. Although the proposal is partly inspired by some of the current knowledge about the structural and functional properties of the mammalian brain, we do not claim that biological systems work in an analogous way (nor the opposite). Based on some properties of the cerebellar cortex and adjacent structures, a proposal suitable for practical problems is presented. A synthetic structure capable of identifying and predicting complex temporal series will be defined and experimentally tested. The system relies heavily on prediction to help identify and learn patterns based on previously acquired contextual knowledge. As a proof of concept, the proposed system is shown to be able to learn, identify and predict a remarkably complex temporal series such as human speech, with no prior knowledge. From raw data, without any adaptation in the core algorithm, the system is able to identify certain speech structures from a set of Spanish sentences. Unlike conventional ML, the proposal can learn with a reduced training set. Although the idea can be applied to a constrained problem, such as the detection of unknown vocabulary in a speech, it could be used in more applications, such as vision, or (by incorporating the missing biological periphery) fit into other ML techniques. Given the trivial computational primitives used, a potential hardware implementation will be remarkably frugal. Coincidentally, the proposed model not only conforms to a plausible functional framework for biological systems but may also explain many elusive cognitive phenomena.

The neural implementation of operant conditioning with few trials is unclear. We propose a Hippocampus-Inspired Cognitive Architecture (HICA) as a neural mechanism for operant conditioning. HICA explains a learning mechanism in which agents can learn a new behavior policy in a few trials, as mammals do in operant conditioning experiments. HICA is composed of two different types of modules. One is a universal learning module type that represents a cortical column in the neocortex gray matter. The working principle is modeled as Modulated Heterarchical Prediction Memory (mHPM). In mHPM, each module learns to predict a succeeding input vector given the sequence of the input vectors from lower layers and the context vectors from higher layers. The prediction is fed into the lower layers as a context signal (top-down feedback signaling), and into the higher layers as an input signal (bottom-up feedforward signaling). Rewards modulate the learning rate in those modules to memorize meaningful sequences effectively. In mHPM, each module updates in a local and distributed way compared to conventional end-to-end learning with backpropagation of the single objective loss. This local structure enables the heterarchical network of modules. The second type is an innate, special-purpose module representing various organs of the brain's subcortical system. Modules modeling organs such as the amygdala, hippocampus, and reward center are pre-programmed to enable instinctive behaviors. The hippocampus plays the role of the simulator. It is an autoregressive prediction model of the top-most level signal with a loop structure of memory, while cortical columns are lower layers that provide detailed information to the simulation. The simulation becomes the basis for learning with few trials and the deliberate planning required for operant conditioning.

It was the winter 1998 and I have just moved to Baltimore from Italy. Ernst Niebur at the Mind Brain Institute, Johns Hopkins University. At the time I was fascinated by the neuroscience of vision, and was trying to learn from neuroscience book how the brain works, how it makes sense of the stream of sensory information. One concept that was absolutely nebulous was how a brain would "learn", or connect the sensory stream data to actionable insights. "Hebbian learning" kept coming up -- a learning theory in neuroscience stating that "neurons that fire together, wire together".

Adversarial examples are a hot research topic in deep learning nowadays. Subtle, often invisible changes in the data can push our networks to make terrible mistakes. We, as human beings, seem to be way more resilient to these perturbations in our sensory inputs (though not totally immune). There is a certain pattern in our deep learning systems. They achieve remarkable things, but they are also at times delicate and brittle.

Abstract: In August of 2021, the Santa Fe Institute hosted a workshop on collective intelligence as part of its Foundations of Intelligence project. This project seeks to advance the field of artificial intelligence by promoting interdisciplinary research on the nature of intelligence. The workshop brought together computer scientists, biologists, philosophers, social scientists, and others to share their insights about how intelligence can emerge from interactions among multiple agents--whether those agents be machines, animals, or human beings. In this report, we summarize each of the talks and the subsequent discussions. We also draw out a number of key themes and identify important frontiers for future research. When building intelligent systems, the need to employ complex systems comprising a large number of more basic components seems inescapable. Brains are composed of billions of neurons, and digital computers are composed of billions of transistors. It is the myriad ...